Interaction Checker
Entries for the current year and the preceding year are shown here. Older entries can be found in the archive.
November has been a busy month for the website team with preparations for the HIV Drug Therapy conference in Glasgow where we celebrated 25 years of hiv-druginteractions.org (you can read more about the celebrations here
Added: Thursday 28 November 2024
Recordings from the Liverpool Masterclass in Antiviral Pharmacology (LMAP) 2023 are now available on the LMAP website. All LMAP recordings (including those from 2020 and 2021) are also available in the videos section of the HIV drug interactions website.
Added: Wednesday 22 November 2023
The following comedications have been added to the interaction checker in response to requests sent by users of the interaction checker:
Added: Wednesday 30 August 2023
A recording of our IAS 2023 symposium "Liverpool Drug Interactions: Beyond Clinical Evidence" is now available to watch.
Click here to watch or access via the "Videos" section on the website.
Panel and Speakers (timings):
Introduction: Gail Matthews (Co-Chair) & Saye Khoo (Co-Chair)<...
Added: Wednesday 16 August 2023
The number of cancer drugs on the interaction checker continues to expand with seven more drugs being added recently. The new drugs are:
Added: Thursday 10 August 2023
Three more comedications have been add to the cancer therapy class on the interaction checker. The new drugs are:
Added: Thursday 27 July 2023
The following comedications have been added to the interaction checker in response to recent requests:
Added: Thursday 29 June 2023
A further seven drugs have been added to the Cancer Therapies on the interaction checker. The latest drugs are:
Added: Wednesday 28 June 2023
A new prescribing resource giving details of the enzyme induction observed with flucloxacillin has been added to the “Interactions Explained” section of the Prescribing Resources page.
Flucloxacillin is an antibiotic which has been shown to induce CYP3A4 in vitro. Several publication...
Added: Tuesday 13 June 2023
Our coverage of cancer therapies in the comedication list continues to grow with these latest additions:
Added: Wednesday 24 May 2023
The list of cancer therapies continues to expand with the following drugs being added to the comedication list:
Added: Tuesday 16 May 2023
We have continued adding new drugs to the Cancer Therapies class of comedications and a further six drugs are now included:
(Details of the first four new comedications can be found here.)...
Added: Wednesday 10 May 2023
Over the next few months we will be working on adding new drugs to the Cancer Therapies class of comedications. The first four new comedications have been added and are shown below:
Added: Wednesday 03 May 2023
Four comedications used in the treatment of prostate cancer have been added to the interaction checker and can be found in the Cancer Therapies class. The new drugs are:
Added: Wednesday 26 April 2023
Two antibiotics – daptomycin and fosfomycin - have been added to the antibacterial class on the interaction checker.
These latest additions take the number of comedications to over 850 and the number of interactions to ~35800.
Added: Thursday 06 April 2023
We have recently undertaken a comprehensive review of the Prescribing Resources section of the website and have updated documents where necessary. Details of the main changes are summarised below.
All the Treatment Selectors and interaction summary tables have been extensively revised and n...
Added: Tuesday 08 November 2022
The Treatment Selectors in the Prescribing Resources section of the website have been revised and expanded. Various new comedications have been added, along with new entries for the HIV drugs fostemsavir, oral cabotegravir and intramuscular cabotegravir/rilpivirine.
In additi...
Added: Friday 22 October 2021
Three new comedications have been added to the interaction checker. Abiraterone and avelumab are listed in the “cancer therapies” class, and calcitonin (for the prevention of bone loss) is listed in the “other” class.
Added: Tuesday 14 September 2021
Three new comedications have been added to the interaction checker in recent weeks. Details of the drugs and the classes in which they can be found are shown below.
Added: Thursday 12 August 2021
Dapivirine (DPV) has been added as an HIV drug in the NNRTI class. Interactions with dapivirine are available on the website checker and iChart app and will soon be added to the PDF tables of interactions. A pharmacokinetic fact sheet for dapivirine is also available in the Prescribing Resources section of t...
Added: Wednesday 21 July 2021
We are pleased to announce that our HIV drug interaction checker is now available in Spanish.
We have been working partnership with Fundación Huésped in Argentina to provide translations of the drug interaction summaries and these can now be accessed via the links on our home and checker pages, or directly from checker.huesped.org...
Added: Friday 16 July 2021
Two new comedications have been added to the interaction checker and "Overview of Interactions" PDFs (in the Prescribing Resources section of the website).
Dapoxetine has been added to the "other" class and yohimbine has been added to the "erectile dysfunction" class.
Added: Tuesday 13 April 2021
Four new comedications have been added to the interaction checker - bulevirtide in the antiviral class, terbutaline in the bronchodilator class, and azilsartan and triamterene in the hypertension/heart failure class.
The PDF files for the "overview of interactions" tables in the
Added: Friday 09 April 2021
Two new comedications have been added to drug list – alirocumab (Praluent®) in the lipid lowering class and desvenlafaxine (Pristiq®) in the antidepressant class.
We have also decided to remove saquinavir from the list of HIV drugs given its very low usage worldwide.
New versions of the PDF charts with these changes are listed under "Overview of Interactions" in the
Added: Friday 26 March 2021
Two new comedications (tazobactam and lenalidomide) have been added to the interaction checker. An update is available for the iChart app and new versions of the "Overview of Interactions" PDF files (found in Prescribing Resources) have been uploaded.
Added: Monday 04 November 2019
Two dolutegravir-containing coformulations have been added to the interaction checker - Dovato® (dolutegravir and lamivudine) and Triumeq® (dolutegravir, abacavir and lamivudine).
The Overview of Interactions in the Prescribing Resources have been updated to include these coformulati...
Added: Monday 22 July 2019
Over the past few weeks we have been working on updating and expanding some of the "Prescribing and Dosing Guidance" files in the Prescribing Resources section of the website.
“Prescribing guidance for elderly PLWH” has been expanded to include two new tables – the top te...
Added: Wednesday 10 July 2019
Four new comedications have been added to the interaction checker and takes the total number of comedications on the website to ~730.
The new comedications and their classes are shown below. An update to the iChart app is available and the PDF files have been updated for the Overview of Interactions in the
Added: Thursday 06 June 2019
Nine new comedications have been added to the interaction checker in response to requests received during the last 12 months or so. This takes the total number of interactions on the website to over 26,000.
The new comedications and their classes are shown below. An update to the iChart app is available and the PDF files have been updated for the Overview of Interactions in the
Added: Tuesday 19 February 2019
Minor revisions have been made to the interaction chart for hormone therapy for gender transitioning. Three new antiretrovirals have been added to the chart - atazanavir alone, doravirine and bictegravir. The interaction chart is listed as a Treatment Selector (by patient characteristic) and can be found in the ...
Added: Friday 15 February 2019
Updated Treatment Selectors (by therapeutic indication) are now available in the Prescribing Resources section of the website.
This has been a major update as one new antiretroviral (doravirine) and four new antiretroviral combinations (atazanavir/cobicistat, darunavir/cobicistat, bictegravir/emtricitabi...
Added: Thursday 14 February 2019
Added: Wednesday 06 December 2017
All comedications have now been reassessed using the new interaction classification system which includes “yellow”. (Yellow interactions are likely to be of weak intensity and not requiring additional action or monitoring, or a dosage adjustment - click here for further details.)
...Added: Tuesday 21 November 2017
The first batch of comedications have been reassessed using the new interaction classification system which includes “yellow” (interactions likely to be of weak intensity and not requiring additional action or monitoring, or a dosage adjustment - click here for further details). Yellow interactions are now included fo...
Added: Wednesday 01 November 2017
Nos populaires tables d’interactions médicamenteuses entre antirétroviraux et différentes classes thérapeutiques sont maintenant aussi disponibles en français et peuvent être téléchargées depuis ce lien.
Les tables d’interactions en français ont été produites pour les classes thérapeutiques su...
Added: Wednesday 08 June 2016
Added: Tuesday 01 December 2015
Added: Monday 17 November 2014
Added: Friday 10 May 2013
Added: Thursday 06 December 2012
Added: Friday 05 November 2010
Many changes and additions have been made to the interactive interactions charts as a result of updates to SPCs and Prescribing Information. New versions of the printed charts and HIV-Charts2Go are available with these changes and additions.
Added: Thursday 06 November 2008
Interactions with maraviroc are now available on the website. Interactions with other HIV drugs have been added as new row to the existing charts.
Added: Wednesday 03 October 2007
Interaction Charts - antimalarial drugs revised and expanded.
Added: Saturday 20 January 2007
Medscape Web Conference
Optimizing Antiretroviral Therapy for HIV: Key Pharmacologic Concerns.
Presenters: David Back, PhD, and Marta Boffito, MD, PhD
In this recent CME/Pharmacist CE program, David Back and Marta Boffito explain pharmacologic information of key importance to HIV clin...
Added: Friday 21 July 2006