Key updates for May and June are shown below. In addition to these changes, a further 19 interactions have been revised due to, for example, updated publications, change of QT risk, and/or enzyme inhibition/induction effect.
New Comedications
Anaesthetics and Muscle Relaxants: Cyclobenzaprine
Antibacterials: Gatifloxacin, Nafcillin, Neomycin, Roxithromycin
Anticoagulants, Antiplatelets and Fibrinolytics: Nadroparin
Anticonvulsants: Felbamate
Antihistamines: Clemastine
Anxiolytics/Hypnotics/ Sedatives: Eszopiclone
Bronchodilators: Zafirlukast
Cough and Cold Preparations: Benzonatate
Gastrointestinal Agents: Docusate
Other: Glacial acetic acid (topical), Phenylephrine, Piracetam, Zileuton
Interaction Colour Changes
↑ Green to yellow:
Telavancin + efavirenz
Telavancin + fostemsavir
Bilastine + efavirenz
Bilastine + rilpivirine
Bilastine + rilpivirine/emtricitabine/tenofovir alafenamide
Bilastine + rilpivirine/emtricitabine/tenofovir-DF
Bilastine + cabotegravir/rilpivirine
Bilastine + dolutegravir/rilpivirine
Bilastine + fostemsavir
↑ Yellow to amber:
Zopiclone + lenacapavir
↑ Amber to red:
Dexamethasone (>16 mg) + bictegravir/emtricitabine/tenofovir alafenamide
↓ Yellow to green:
Bosentan + bictegravir/emtricitabine/tenofovir alafenamide
Bosentan + dolutegravir
Bosentan + dolutegravir/lamivudine
Bosentan + dolutegravir/abacavir/lamivudine
Bosentan + dolutegravir/lamivudine/tenofovir-DF
↓ Red to amber:
Rifampicin + atazanavir/ritonavir
